VOTW: Tube-y or not Tube-y: Two Cases of Ectopic Pregnancy

Case 1

33-year-old female G3P1, LMP 7 weeks ago, with a history of ectopic pregnancy, which was medically managed, presenting with 1 day of vaginal bleeding. Beta-hCG 5200. 

Transvaginal pelvic ultrasound showed no definitive intrauterine pregnancy and a cystic structure in the left adnexa by the ovary.

In the perinatal unit, ultrasound by MFM confirmed an ectopic pregnancy with a visible fetal heart rate. The patient underwent laparoscopy and salpingectomy that showed a dilated left fallopian tube and had a small amount of intraoperative blood loss. 


Case 2

36-year-old female G4P2, LMP 3 weeks ago, presenting with lower abdominal pain after a bowel movement, followed by vaginal bleeding. Beta-hCG was 230. 

Transvaginal pelvic ultrasound showed no definitive intrauterine pregnancy and a moderate to large amount of free fluid.

The patient underwent diagnostic laparoscopy with salpingectomy. 300 mL of hemoperitoneum was found intraoperatively, and the patient was diagnosed with a left ruptured tubal ectopic pregnancy.

Ectopic pregnancy on ultrasound

Approach

  • Start with the curvilinear probe and switch to the endocavitary probe if better resolution is needed

  • In a patient of childbearing age with abdominal pain and hypotension, start with a FAST exam to look for free fluid in Morison’s pouch

Findings suggestive of ectopic pregnancy

  • Empty uterine cavity or intrauterine fluid without a yolk sac

  • Abdominal free fluid 

  • A “tubal ring” appearance, an echogenic ring that surrounds an unruptured ectopic pregnancy (n.b. this can be mimicked by a normal corpus luteum). See structure marked by arrow in image above. 

  • Less than 5 mm of myometrium surrounding an eccentrically located gestational sac. This is a type of ectopic pregnancy called an interstitial pregnancy.

References

Happy scanning!

US team


VOTW: Interstitial Ectopic Pregnancy

This week’s VOTW is brought to you by… none other than our fantastic ED Medical Director Dr. Nubaha Elahi and Dr. Waters!

A 44 year old female G5P3 w/ hx of Essure procedure (a 99.3% effective method of contraception) presented to the ED with bilateral eye swelling x1 week. She also had a positive home pregnancy test and vaginal spotting. Without being mislead by the initial chief complaint on a busy fast-track shift the team performed a POCUS of the pelvis which showed...

Clip 1 shows a transabdominal view of the uterus with an empty gestational sac and a thick walled complex R adnexal cyst/mass. In the setting of a bHCG of 37000, this is concerning for an ectopic pregnancy!

Clip 2 shows a transvaginal view of the uterus with an eccentrically located gestational sac containing a fetal pole. Given the concern for interstitial ectopic, the team measured the endomyometrial mantle thickness (nice!) which was 1cm (still within normal range, however approaching the 8mm cutoff).

**The Essure procedure involved inserting metal coils in bilateral fallopian tubes to cause scarring. In 2018 it was taken off of the market because it was associated with many complications including ecotpic pregnancies. 

Endomyometrial mantle thickness measurement

Interstitial ectopic

An interstitial ectopic is a pregnancy implanted in the myometrium. It carries a higher rate of shock and hemoperitoneum and higher maternal mortality compared to the other ectopic pregnancies due to the highly vascular myometrium (1)

Think about interstitial ectopic pregnancy if you see an eccentrically placed gestational sac and measure the EMM.

Endomyometrial mantle (EMM) measurement

  • EMM = thickness of the endometrium + myometrium

  • Measure from outer edge of the gestational sac to outer edge of the uterus at the THINNEST portion that you see (image 1)

  • EMM <8mm is concerning for an interstitial ectopic pregnancy

Back to the patient

OBGYN was consulted who admitted the patient for a laparoscopic hysterectomy. The final diagnosis was right interstitial ectopic pregnancy!

We’ve reviewed many ectopic pregnancy cases caught on POCUS recently- an example of a diagnosis where POCUS truly is saving lives! Keep up the great work!

References:

  1. Rastogi R, Gl M, Rastogi N, Rastogi V. Interstitial ectopic pregnancy: A rare and difficult clinicosonographic diagnosis. J Hum Reprod Sci. 2008 Jul;1(2):81-2. doi: 10.4103/0974-1208.44116. PMID: 19562051; PMCID: PMC2700669.