Pearl of the Day: Otitis Externa

Otitis Externa (OE) Etiology - Pseudomonas aeruginosa, Staphylococcus aureus - occurs with conditions that alter the normal external ear canal flora (e.g., exposure to moisture, direct trauma to ear)

Signs/Symptoms - early stages:  ear fullness, itching - erythematous ear canal, tender pinna and tragus - pain exacerbated by manipulation of auricle or range of motion of TMJ - usually normal tympanic membrane

Diagnostic Criteria - rapid onset within 48 hours in the past 3 weeks of at least one primary symptom (otalgia, itching, fullness) AND - one primary sign (tenderness of tragus/pinna or diffuse ear canal edema/erythema)

Treatment - attempt to remove debris to increase efficacy of topical medication - steroid-antibiotic combination drops (e.g., ciprofloxacin with dexamethasone) - for mild OE (without TM perforation), may use acidifying therapy (e.g., boric acid, acetic acid) - cotton wick can be placed to get drops deeper toward tympanic membrane

Cotton Wick - can be made from narrow gauze (0.25 inch packing) or from hard sponge material that expands (e.g., Merocel) - medication is placed onto external end of ear wick, which is then pulled into the ear canal - antibiotic drops should be placed 2 - 4 times daily - may fall out as edema decreases - should be removed after 2 - 3 days

Surgical Debridement and Drainage - reserved for necrotizing OE, complications of OE, significant amount of discharge, fungal infections - failure of prolonged antibiotic therapy

Systemic Antibiotics - only for extension of disease outside of ear canal and/or host is immunocompromised - if started, should consider cultures of ear canal

Complications - external canal stenosis - requires debridement - abscess formation (usually with S. aureus infections) - requires I&D by ENT - malignant OE/necrotizing OE from P. aeruginosa caused by local invasion into skull and underlying structures

Discharge Instructions - keep ear canal dry - place earplug or cotton ball coated with petroleum jelly in ear canal when bathing/showering - may resume aquatic activities once infection is treated (usually 4 - 5 days)

Resources https://emedicine.medscape.com/article/994550 Peer IX Tintinalli's Emergency Medicine, 8th Edition

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Pearl - Corticosteroid Use in the Pediatric ED.

Source: ebmedicine.net

-A single dose of dexamethasone in the ED is efficacious for asthma exacerbation, and particularly valuable when patient/family compliance is a concern.
-There is no proven efficacy for giving corticosteroids in the setting of anaphylaxis; this should not delay epinephrine administration.
-In patients with bacterial meningitis, corticosteroids should ideally be administered before antibiotics, however, some sources support their administration up to 4 hours after antibiotics.
-Caution is indicated in patients with hypercoagulable states and bacterial meningitis, due to one citation suggesting the possible increased risk of central venous thrombosis.
-Patients on chronic steroids, immunodeficiency, or those with adrenal suppression, may require higher or additional doses of steroids and may not respond to standard dosing.
Thanks for reading,
Vish
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Trauma Tuesday - Why crash-2 and women matter.

Pearl -Tranexamic Acid (TXA) for the Hemorrhaging Trauma Patient

Early TXA administration has been shown to decrease deaths from acute severe bleeding. It works by inhibiting the breakdown of fibrin thus preserving the clot matrix. A 1g loading dose over 10 mins and another 1g over 8 hrs may reduce mortality.
Coming soon, the CRASH-3 trial, which evaluates its use in patients with TBI. http://crash3.lshtm.ac.uk/
WOMAN - http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)30638-4/fulltext
MATTERs - https://www.ncbi.nlm.nih.gov/pubmed/22006852
CRASH-2 - https://www.ncbi.nlm.nih.gov/pubmed/23477634
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